Amy Locane was born in Trenton, New Jersey, and raised by her mother. She was ten years old when a local photographer spotted her and sent her picture to an agent in New York. Amy commuted to New York, accompanied by her mother, and auditioned for commercials, often doing her homework on the train. By the time she was 12, she had 50 commercials under her belt and landed her first sitcom, Spencer (1984) on NBC, playing Chad Lowe's younger sister. When she was 16, she won her first role in a film, Le carrefour des innocents (1989) in which she starred opposite Donald Sutherland for Oscar-winning director Hugh Hudson. Other films quickly followed, including the cult classic Cry-Baby (1990) starring Johnny Depp and directed by John Waters, La différence (1992) starring Ben Affleck and Matt Damon and Tony Richardson's Blue Sky (1994), in which she won critical raves playing Jessica Lange's daughter.
When she was 19, Aaron Spelling picked her to be in the original cast of Darren Star's Melrose Place (1992). Unfortunately, all the other actors were in their mid to late 20s, and the young Locane was evicted after only 13 episodes.
After Melrose Place (1992), she looked for edgier roles and found them in indie films, including a supporting role to Maggie Gyllenhaal in La secrétaire (2002). In 2006, she retired from films and moved back to her New Jersey hometown, where she married a local businessman and had two daughters.
