Sana Saeed who currently resides in Leeds, England, was chosen among two-hundred other children to play Shahrukh Khan's daughter in Laisse parler ton coeur (1998), her only movie besides Badal (2000) and Har Dil Jo Pyar Karega... (2000) in which she reprised her role from Laisse parler ton coeur (1998) as the little Anjali in a guest appearance. Prior to Laisse parler ton coeur (1998) she had refused Rahul Gupta's Hum Panchi Ek Daal Ke, since she could not continue studying while shooting it; so Laisse parler ton coeur (1998) was shot during her school vacation. She won the Sansui Viewers' Choice Award as the best Child Artist for it.
Her favorite scene in Kuch Kuch Hota Hai is when Shahrukh Khan's character forgets his trousers and she herself thinks her performance during the elocution scene "was not that great."
Currently, she is a signed model for Benchmark Models.